Aortic lipolytic activity in 24-month and 2- to 3-month male rats is significantly lower than that of 7-month rats. of ageing, but an independent pathological entity. In man, lipolyticNo significant differences in myocardial lipolytic activity were found activity is probably not the only factor in the pathogenesis ofin these animals. Atherosclerosis is not considered a necessary part atherosclerosis.