ACETYLCHOLINE IN OPHTHALMOLOGY AND THE TREATMENT OF OCULAR PAIN
- 1 October 1942
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 28 (4) , 599-612
- https://doi.org/10.1001/archopht.1942.00880100033003
Abstract
ACETYLCHOLINE IN OPHTHALMOLOGY Acetylcholine was first prepared in 1867 by Baeyer,1 but it was not until 1906 that Hunt and Taveau2 discovered its action on the circulation. Another twenty years passed before the drug was clinically investigated by Villaret and Justin-Besançon;3 I believe it was first used by them in 1926 in a case of Raynaud's disease. During the next fifteen years it was widely used in France, and like most new medicines it went through an initial period when it was tried in the treatment of various diseases and a second one when the boom was over and when experience had shown in what diseases and in what selected cases it could be helpful. Pharmacodynamics.4 —Acetylcholine derives from choline and is normally found in many tissues of the body, as it is liberated at the nerve endings in vagal or parasympathetic nerve impulses. Inversely, theThis publication has 0 references indexed in Scilit: