Antibody Response to Poliomyelitis Vaccine Administered by Jet Injection

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Abstract
A multiple-dose jet injection apparatus was tested in a group of 34 children for its effectiveness as a method of administering poliomyelitis vaccine. Twenty-seven children served as controls and received the same vaccine by syringe and needle at the same time. Serum specimens obtained prior to the 1st injection of vaccine and one month following the 2d dose were tested for poliomyelitis antibody. The results indicate that antibody response following jet injection was as great as after the standard method of vaccine administration. Comments are made concerning advantages and disadvantages of the machine.