Abstract
The source of increased plasma alkaline phosphatase activity in laying hens following thyroprotein feed supplementation was investigated in the liver, kidney, duodenum, jejunum, ileum, uterus and femur. Enzyme activity was found to be the most responsive in the duodenum and bone; response in the bone was almost twice as high as in the control group. The epiphyseal parts of the bone showed the greatest relative response as compared with the cortical or medullary parts, though the absolute highest activity was found in the latter. It seems, therefore, that the bone serves as the main source of increased plasma alkaline phosphatase activity in hyperthyroid laying hens.

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