Abstract
In a 5‐year delivery series of 19,422 cases lending itself well to epidemiologic studies, the aplasia of one umbilical artery was present in 0.27 %. Of these, 32% had other congenital malformations. In those cases, where one umbilical artery was missing without other congenital malformations, there was no increased incidence of prematurity but an increased incidence of low birth weight was present, which, however, was not statistically significant. If the aplasia of the umbilical artery was combined with other congenital malformations, a clear prematurity and a significant low birth weight were present. The anomaly was equally frequent for primiparae and multiparae. No seasonal variation was found. It is plausible to suggest from some of the cases of this series that both exogenic agens and hereditary factors can cause absence of one umbilical artery.

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