SOMATOMEDIN GENERATING ACTIVITY OF THE 20,000-DALTON VARIANT OF HUMAN GROWTH HORMONE
- 1 October 1981
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 109 (4) , 1301-1302
- https://doi.org/10.1210/endo-109-4-1301
Abstract
The 20,000-dalton variant of human growth hormone stimulated production of somatomedins in the hypophysectomized rat. Somatomedin activity was measured by a radioreceptor assay. The results indicate that the insulin-like activities of human growth hormone that are greatly diminished in the variant are not prerequisites for somatomedin production.Keywords
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