Comparison of Single Dose with a 5‐day Course of Co‐trimoxazole for Asymptomatic (Covert) Bacteriuria of Pregnancy
- 1 August 1983
- journal article
- clinical trial
- Published by Wiley in Australian and New Zealand Journal of Obstetrics and Gynaecology
- Vol. 23 (3) , 139-141
- https://doi.org/10.1111/j.1479-828x.1983.tb00562.x
Abstract
Summary: Forty‐four pregnant women with covert (asymptomatic) bacteriuria proven by suprapubic bladder aspiration were randomly allocated to treatment with either a single 1.92g dose or a standard 5‐day course of co‐trimoxazole. Twenty‐one of 24 women were cured with a single dose. Seven of these 21 women were reinfected later in the pregnancy. All 20 women treated with a 5‐day course of co‐trimoxazole were cured, and 2 became reinfected later in the pregnancy. There were no side‐effects of treatment, and no detrimental effects on the outcome of pregnancy. Single dose therapy should be considered as the treatment of choice for covert bacteriuria in pregnancy.Keywords
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