As A RESULT of our experience with a patient who had three - attacks of uremia with as high as 20 lymphocytes per cubic millimeter of spinal fluid during each episode, cell counts were made in 62 consecutive cases of uremia. Patients with a history or findings of syphilis or with any condition that could result in pleocytosis were not included in the series. In the last 30 cases examination was also made for the presence of meningeal signs. In 58 of the 62 cases the uremia was due to renal disorders and in 4 to gastric hemorrhages with prerenal azotemia. The urea content of the blood was calculated from the urea nitrogen determined by the aeration-titration method. The urea value of the cerebrospinal fluid was similarly determined from specimens drawn at the same time as the blood in 29 cases. An increase in cells in the spinal fluid has been