Electron Microscopy of Cartilage Resorption by Chondroclasts

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Abstract
Cartilage resorption by the chondroclasts during the intracartilaginous bone formation in phalangeal bones of young mice was studied with the electron microscope. The occurrence of the cartilage matrix fibrils denuded of crystals as well as free crystals liberated from the matrix were indicated in the chondroclasts and at the edge of the resorbing cartilage. An increase in the electron density suggested to be the result of an alteration in the organic matrix of the cartilage was observed beneath the area that had been changed into a porous structure because of active resorption.