The etiology and pathogenesis of the so-called idiopathic scleroses and atrophies of the skin is still such a mystery, and the classification is in many ways so unsatisfactory, that the record of a case which presents such a variety of symptoms as occurred in the patient about to be described may be of interest and perhaps of value. REPORT OF A CASE History.— E. G., an American girl, aged 12, was admitted to the New York Skin and Cancer Hospital on Oct. 26, 1922, with a diagnosis of scleroderma. The family history was negative for tuberculosis and syphilis. The patient had had scarlet fever when about 4 years of age, with uneventful recovery, and measles in May, 1918, when about 7½ years old. Soon after recovery from measles, the patient said, she had a sore mouth, involving the buccal and labial mucous membrane, and lasting about two weeks. This seems