Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease
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Open Access
- 20 January 2010
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 303 (3) , 250-257
- https://doi.org/10.1001/jama.2009.2008
Abstract
Multiple epidemiologic studies, including several large randomized controlled trials, have demonstrated higher survival rates among individuals with high dietary intake of marine omega-3 fatty acids and established cardiovascular disease.1-4 On this basis, the American Heart Association recommends increased oily fish intake and the use of omega-3 fatty acid supplements for the primary and secondary prevention of coronary heart disease.5 The mechanisms underlying this protective effect are poorly understood but are thought to include anti-inflammatory, antiplatelet, antihypertensive, antiarrhythmic, and triglyceride-lowering effects.6 There is ongoing interest in the identification of novel mechanisms of cardiovascular benefit from omega-3 fatty acids.Keywords
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