8-Chloro-cAMP inhibits transforming growth factor alpha transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase regulatory subunit isoforms which show disruption upon transformation.
Open Access
- 4 January 1990
- journal article
- abstracts
- Published by Elsevier
- Vol. 265 (2) , 1016-1020
- https://doi.org/10.1016/s0021-9258(19)40152-x
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Site-Selective 8 -Chloro- Cyclic Adenosine 3′,5′-Monophosphate as a Biologic Modulator of Cancer: Restoration of Normal Control MechanismsJNCI Journal of the National Cancer Institute, 1989
- Human testis cDNA for the regulatory subunit RIIα of CAMP‐dependent protein kinase encodes an alternate amino‐terminal regionFEBS Letters, 1989
- Site‐selective 8‐chloroadenosine 3′,5′‐cyclic monophosphate inhibits transformation and transforming growth factor α production in Ki‐ras‐transformed rat fibroblastsFEBS Letters, 1989
- Transformation of an established mouse mammary epithelial cell line following transfection with a human transforming growth factor alpha cDNAMolecular Carcinogenesis, 1989
- Transforming growth factor αCell, 1988
- Site‐selective cyclic AMP analogs provide a new approach in the control of cancer cell growthFEBS Letters, 1987
- The TGF-β family of growth and differentiation factorsCell, 1987
- Immunological detection and quantitation of alpha transforming growth factors in human breast carcinoma cellsBreast Cancer Research and Treatment, 1986
- Activation of protein kinase isozymes by cyclic nucleotide analogs used singly or in combinationEuropean Journal of Biochemistry, 1985
- Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseBiochemistry, 1979