Removal of Bilirubin by Albumin Binding during Intermittent Peritoneal Dialysis

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Abstract
Since the introduction of intermittent peritoneal dialysis by Grollman et al.1 in 1951 a number of reports have appeared attesting to its efficacy in the removal of dialyzable substances in acute renal failure,2 3 4 5 hypercalcemia,4 barbiturate intoxication,4 salt poisoning,6 salicylism7 and hepatic coma.8 The toxic substances involved in these conditions are water soluble and freely dialyzable. Bilirubin, however, is poorly soluble in water and is almost entirely bound to protein in icteric serum.9 The present report of a case of an unusual combination of acute hepatitis, drug-induced hemolytic anemia and renal failure describes the accelerated removal of bilirubin induced by the . . .

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