Synthesis of glucosylceramide analogues: imino-linked 5a-carbaglycosylceramides, potent and specific glucocerebrosidase inhibitors

Abstract
Imino-linked carbocyclic analogues (E)- and (Z)-2 of glucosylceramide 1 have been synthesized and shown to be potent and specific inhibitors against glucocerebrosidase.

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