Refection in rats fed on a sucrose-based, riboflavin-deficient diet
- 1 January 1980
- journal article
- research article
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 43 (1) , 171-177
- https://doi.org/10.1079/bjn19800076
Abstract
1. Refection, resulting in an increased supply of riboflavin to riboflavin-deficient rats through coprophagy, was demonstrated on a sucrose-based diet when sensitive biochemical tests of riboflavin status were employed: these included measurements of NAD(P)H2:glutathione oxidoreductase (EC1.6.4.2); succinate:(acceptor) oxidoreductase (EC1.3.99.1) and NADH:(acceptor) oxidoreductase (EC1.6.99.3).2. The use of tail-cups to eliminate coprophagy, and hence refection, resulted in a more rapid and reproducible progress into severe deficiency.3. The occurrence of refection on a sucrose-based diet may account for hitherto unexplained differences between previous publications on the biochemical effects of riboflavin deficiency.This publication has 22 references indexed in Scilit:
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