Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer
- 11 January 2008
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 16 (6) , 2764-2768
- https://doi.org/10.1016/j.bmc.2008.01.012
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Future therapies in hormone-refractory prostate cancerUrology, 2005
- Hedgehog signalling in prostate regeneration, neoplasia and metastasisNature, 2004
- Modulation of Notch Processing by γ-Secretase Inhibitors Causes Intestinal Goblet Cell Metaplasia and Induction of Genes Known to Specify Gut Secretory Lineage DifferentiationToxicological Sciences, 2004
- Hedgehog signalling in cancer formation and maintenanceNature Reviews Cancer, 2003
- Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumoursNature, 2003
- Sonic Hedgehog Is Required for Progenitor Cell Maintenance in Telencephalic Stem Cell NichesNeuron, 2003
- Gli and hedgehog in cancer: tumours, embryos and stem cellsNature Reviews Cancer, 2002
- Sonic hedgehog regulates gastric gland morphogenesis in man and mouseGastroenterology, 2001
- Concentration of enzymatically active prostate‐specific antigen (PSA) in the extracellular fluid of primary human prostate cancers and human prostate cancer xenograft modelsThe Prostate, 2001
- In Vivo activity of a PSA-activated doxorubicin prodrug against PSA-producing human prostate cancer xenograftsThe Prostate, 2000