Somatostatin does not reduce oesophageal variceal pressure in liver cirrhotics.
Open Access
- 1 February 1988
- Vol. 29 (2) , 153-156
- https://doi.org/10.1136/gut.29.2.153
Abstract
Transmural oesophageal variceal pressure was determined by direct puncture of the varices in 27 patients with liver cirrhosis and oesophageal varices. Variceal pressure was not influenced three to six minutes after somatostatin bolus administration and slightly increased during somatostatin infusion. Thus, potential haemostatic benefits of somatostatin cannot be explained by pressure reductions in the varices.This publication has 11 references indexed in Scilit:
- Effect of somatostatin on oesophageal variceal pressure assessed by direct measurementJournal of Hepatology, 1986
- Prognostic Significance of Serum Bile Acids in CirrhosisHepatology, 1986
- Effects of a somatostatin analogue SMS 201-995 on hepatic haemodynamics in the pig and on intravariceal pressure in manBritish Journal of Surgery, 1985
- Intravascular oesophageal variceal pressure (IOVP) assessed by endoscopic fine needle puncture under basal conditions, Valsalva's manoeuvre and after glyceryltrinitrate application.Gut, 1985
- A prospective randomised controlled clinical trial comparing somatostatin and vasopressin in controlling acute variceal haemorrhage.BMJ, 1985
- Effect of somatostatin on splanchnic hemodynamics in patients with cirrhosis of the liver and in normal subjectsGastroenterology, 1981
- Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: Comparison with vasopressinGastroenterology, 1981
- Somatostatin Not Helpful in Bleeding Esophageal VaricesNew England Journal of Medicine, 1979
- Treatment of bleeding oesophageal varices with somatostatin.1979
- Transection of the oesophagus for bleeding oesophageal varicesBritish Journal of Surgery, 1973