IMMUNOLOGY OF CHRONIC GASTRITIS

1 January 1981

journal article
research article

Vol. 13 (3) , 130-132

Abstract

Sixty-five patients with chronic gastritis and 12 controls with normal gastric mucosa were studied for cell-mediated immunity by the lymphocyte blast transformation and leukocyte migration inhibition tests. In these patients parietal cell antibodies were determined by the indirect immunofluorescence test. In 22 patients who had isolated fundal gastritis, isolated antral gastritis or pangastritis, cellular immune reactions to fundal or/and antral mucosal antigen extracts were revealed; only 8 had parietal cell antibodies in their sera. For immunological characterization of chronic gastritis the evaluation of cellular immune reactions and antibody determinations must be undertaken.

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