FATAL LIVER NECROSIS AND DIPHENYLHYDANTOIN SENSITIVITY
- 1 October 1962
- journal article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 30 (4) , 595-600
- https://doi.org/10.1542/peds.30.4.595
Abstract
The findings in a fatal case of liver necrosis in a child given diphenylhydantoin sodium are presented. Typical lymph node hyperplasia of the reticulum cells, with mitotic figures and eosinophils, were seen in this instance. These are a well-documented finding in hypersensitivity to this drug.Keywords
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