Technique for the Deposition of Macromolecular Samples in Field Emission and Field Ion Microscopy
- 1 August 1965
- journal article
- Published by AIP Publishing in Review of Scientific Instruments
- Vol. 36 (8) , 1233-1236
- https://doi.org/10.1063/1.1719845
Abstract
The technique involves the freezing on the microscope tip of a droplet of solution containing the subject molecules, followed by freeze drying. Alternate hypotheses concerning the delivery mechanism during freeze drying, and thus estimates of required specimen concentrations in solution, are evaluated by comparing them with experimental results obtained for copper phthalocyanine (10 mg/ml), transfer RNA (1 mg/ml), and light meromyosin (10−3 mg/ml).Keywords
This publication has 3 references indexed in Scilit:
- A method of freeze-drying for electron microscopyExperimental Cell Research, 1953
- Ultra-microtomy by a new methodJournal of Research of the National Bureau of Standards, 1949
- Frozen-Dried Preparations for the Electron MicroscopeScience, 1946