Gastrointestinal mast cells in health, and in coeliac disease and other conditions.
Open Access
- 1 September 1980
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 55 (9) , 702-705
- https://doi.org/10.1136/adc.55.9.702
Abstract
Intestinal biopsies were performed in children suffering from coeliac and other diseases and were stained by the 'astra-blau' method for visualising granulated mast cells. The density of granulated mast cells (per microscopical field) in treated coeliac disease and in 3 control groups (patients suffering from milk allergy, failure to thrive, or protracted diarrhoea) was 15--18 cells per microscopical field, which contrasted with a mean of 6.8 cells in untreated coeliac disease. It is concluded that exposure to gluten in coeliac disease results in degranulation of mast cells, while exposure to milk in milk allergy has no such effect.This publication has 17 references indexed in Scilit:
- Distribution and valency of receptor for IgE on rodent mast cells and related tumour cellsNature, 1976
- Mast cells and immunoglobulin E in inflammatory bowel disease.Gut, 1975
- Current concepts on the secretory function of mast cellsLife Sciences, 1975
- THE SMALL-INTESTINAL MUCOSA IN COW'S MILK ALLERGYThe Lancet, 1975
- Basophils in bronchial asthma with reference to reagin‐type allergyClinical and Experimental Allergy, 1973
- Contributions of Electron Microscopy to the Study of Mast CellsJournal of Investigative Dermatology, 1972
- Mast cells in health and disease.1968
- MILK ALLERGY. I. ORAL CHALLENGE WITH MILK AND ISOLATED MILK PROTEINS IN ALLERGIC CHILDREN.1963
- MAST CELLS AND THE GASTROINTESTINAL TRACT - REVIEW1960
- The copper phthalocyanin dye ?Astrablau? and its staining properties, especially the staining of mast cellsHistochemistry and Cell Biology, 1960