Lindau's Disease

Abstract
ARVID LINDAU (born in 1892), Swedish pathologist, made an important contribution to neurology with a detailed analysis of a unique disorder now known as Lindau's disease.1 The fully developed disease includes cerebellar and retinal hemangioblastomas with cysts and neoplasms of the kidney, pancreas, and adrenal gland. Various manifestations of the disorder had been described as isolated findings for at least 50 years before Lindau's work, but he recognized them as variable features of a single underlying process. Lindau's exhaustive study, published in 1926,2 begins with a 24-page historical review of cerebellar cysts. The author's cases are then presented, with emphasis on the tumor subsequently named the hemangio-blastoma, and the relevant medical literature is thoroughly reviewed. There follows a discussion of angiomatosis retinae (von Hippel's disease3-5) and its relationship to the intracranial hemangioblastomas, a topic that Lindau presented again the following year.6 Additional experience since 1926

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