Identification of histological features associated with metastatic potential in thin (<1.0 mm) cutaneous melanoma with metastases. A study on behalf of the EORTC Melanoma Group
- 22 March 2002
- journal article
- research article
- Published by Wiley in The Journal of Pathology
- Vol. 197 (2) , 188-193
- https://doi.org/10.1002/path.1093
Abstract
An Erratum has been published for this article in The Journal of Pathology 197(5) 2002, 692. Contrary to expectations, a small number of thin (3 per mm2) were much more common in the metastasizing lesions (p=0.007). These findings support the idea that in most cases, regression and/or a VGP are required for metastasis to occur. However, a small number of thin melanomas without these features, as conventionally described, still metastasize. This implies that VGP may require redefinition and that junctional expansion nodules and melanomatous follicular invasion may be variants of VGP. Copyright © 2002 John Wiley & Sons, Ltd.Keywords
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