THE EFFECT OF AGE ON THE PHARMACOKINETICS OF OXPRENOLOL

  • 1 January 1982
    • journal article
    • research article
    • Vol. 20  (3) , 101-104
Abstract
The pharmocokinetics of oxprenolol [a .beta.-blocker] were studied in young and healthy elderly volunteers. Drug concentrations in plasma and urine were measured after a single 80-mg dose of oxprenolol and again after repeated administration (80 mg twice/day) for a period of 1 wk. Evidently, multiple dosing does not result in oxprenolol accumulation in either group and age has no effect on the pharmacokinetics of this drug.