Antiplasmodial Activities and Cytotoxic Effects of Aqueous Extracts and Sesquiterpene Lactones fromNeurolaena lobata*

Publisher Website
Google Scholar
Abstract
Aqueous and lipophilic extracts of Neurolaena lobata (Asteraceae), obtained from Guatemala, were tested against Plasmodium falciparum in vitro. Moreover, sesquiterpene lactones, of the germacranolide and furanoheliangolide type, isolated from N. lobata, were shown to be active against P. falciparum in vitro. In addition to their antiplasmodial activity, their cytotoxic effects on human carcinoma cell lines were evaluated. Structure-activity relationships are discussed.

This publication has 0 references indexed in Scilit: