Changes in activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits and accumulation of crossreacting immune material.
- 1 December 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (12) , 6323-6325
- https://doi.org/10.1073/pnas.76.12.6323
Abstract
The activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits decreases to less than 1/2 the value found in livers of fed rabbits. The concentration of aldolase protein in the liver extracts, measured with a specific antibody, remains unchanged. More than twice as much antibody is required to neutralize the adolase activity in liver extracts from fasted compared with fed rabbits. Modification of liver aldolase apparently occurs during fasting, resulting in loss of catalytic activity without loss of immunoreactivity.This publication has 15 references indexed in Scilit:
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