The effect of cigarette smoke on the plasma piroxicam concentrations in rats
- 1 November 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 42 (11) , 802-803
- https://doi.org/10.1111/j.2042-7158.1990.tb07026.x
Abstract
The plasma concentration of unchanged piroxicam has been determined at 15, 30, 60 and 90 min after 10 mg kg−1 oral administration of the drug to rats exposed to cigarette smoke or pretreated with phenobarbitone, 3,4-benzpyrene or ethanol. Plasma piroxicam concentrations decreased in rats pretreated with phenobarbitone, 3,4-benzpyrene and ethanol and in rats 24 h after exposure to cigarette smoke.This publication has 15 references indexed in Scilit:
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