Abstract
Selection for early maturation applied to a laboratory colony of Musca domestlca eliminated autosomally controlled DDT-resistance from both sexes, but a proportion of the males exhibited a genetically new type of resistance which was shown to be not transmitted through the females but to involve the Y-chromosome. By a single selection with DDT, applied to males only, the early-maturing strain was separated into 2 true-breeding strains homogeneous in both sexes with respect to DDT-toleranees, the one susceptible to DDT in both males and females, the other susceptible in females but showing at least an eightfold resistance to DDT in all its males.