C-Tumours and polyploidy induced by some alkaloids of opium and cannabis.

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Abstract
Papaverine hydrochloride induces c[colchicine-induced]-tumors in root tips of Allium cepa. Two types of enlargements were noted, complete swelling along the majority of the root and complete swelling with a certain enlargement immediately after the 2 mm terminal tips. These swellings were due to cell enlargement both in meristematic and in tumor zones. Papaverine hydrochloride and morphine sulfate showed roughly polyploid roots as the concentration of the chemical increased. The effect of cannabis dissolved in water on the rate of polyploid induction varied according to the concentration applied.

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