The partition separation of tropane alkaloids

Abstract
Data on the partition of tropane alkaloids between an aqueous buffer phase, of varied pH, and chloroform are presented in terms of the pH at which 50 per cent. extraction occurs. The true distribution coefficient of some of the alkaloids is derived from the data. The effect of varying the organic phase has been studied. From the data obtained, the operation of an analytical partition chromatography column is described.

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