AVITAMINOSIS-A AND THE SALIVARY CONDITIONED REFLEX INDUCED BY MORPHINE

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Abstract
Dogs with salivary fistulae conditioned to morphine showed a depression of the conditioned salivary secretion when vitamin A was withdrawn from the otherwise adequate diet. The unconditioned secretion, as measured by the present methods, was decreased comparatively insignificantly. Although the diet was proved to be vitamin A free for rats, it failed to produce deficiency symptoms in the dogs. Anorexia and adipsia did not function in the mechanism of depression. This mechanism was considered a non-specific one depending upon the sensitiveness of the new, conditioned center to untoward influences.

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