EVIDENCE FOR GENETIC-CONTROL OF ANTIBODY AFFINITY FROM BREEDING STUDIES WITH INBRED MOUSE STRAINS PRODUCING HIGH AND LOW AFFINITY ANTIBODY
- 1 January 1976
- journal article
- research article
- Vol. 30 (6) , 789-797
Abstract
The ount (Abt) and relative affinity (KR) of antibody produced in response to protein antigens injected in saline was measured in the parents, F1 hybrids and backcross offspring of inbred mice which produce high and low KR antibody to these antigens. Antibody affinity is under polygenic control. Furthermore, strain related variation in Abt is independent of KR and the breeding experiments indicate that these 2 parameters are under independent genetic control.This publication has 20 references indexed in Scilit:
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