Histiocytosis X: Successful Treatment with Recombinant Interferon‐αA

Abstract
Two patients with disseminated histiocytosis X were treated with intramuscular injections of recombinant interferon αLA. The bone, skin and visceral lesions of these patients diminished rapidly. Significant sclerosis and recalcification of bone were observed. From our limited but positive experience, it would be justified to consider the use of interferon in patients with disseminated histiocytosis X.