Preparation of di‐(2‐ethylhexyl) adipate and some of its metabolites labelled with deuterium
- 1 October 1992
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 31 (10) , 821-828
- https://doi.org/10.1002/jlcr.2580311012
Abstract
The syntheses of deutero‐labelled di‐(2‐ethylhexyl)adipate (DEHA), mono‐(2‐ethylhexyl) adipate (MEHA), 2‐ethylhexan‐1‐ol, 2‐ethylhexanoic acid, 2‐ethyl‐5‐ketohexanoic acid, 3‐ethyl‐6‐methyltetrahydro‐2H‐pyran‐2‐one and 2‐ethylhexanedioic acid are described. All compounds were perdeutero‐labelled in the ethyl group. The title compound, DEHA, was used in a human dosing study.Keywords
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