Serum Inhibitor in Systemic Lupus Erythematosus Associated With Aplastic Anemia
- 1 July 1984
- journal article
- case report
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 144 (7) , 1474-1477
- https://doi.org/10.1001/archinte.1984.00350190172030
Abstract
• Hematologic complications of systemic lupus erythematosus (SLE) usually involve peripheral destruction of blood elements. We report a case of SLE-associated aplastic anemia in which an IgG complement-dependent antibody, obtained from the patient's disease-phase serum but not remission-phase serum, suppressed growth of granulocyte-macrophage progenitor cells from bone marrow of normal donors in vitro. Therapy with plasmapheresis and immunosuppression resulted in lasting remission. (Arch Intern Med 1984;144:1474-1477)Keywords
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