Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes
- 1 October 1984
- journal article
- Published by Springer Nature in Nature
- Vol. 311 (5985) , 438-442
- https://doi.org/10.1038/311438a0
Abstract
Transfer of mouse or human c-fos proto-oncogenes into F9 teratocarcinoma stem cells results in expression of c-fos mRNA and protein. This is accompanied by the appearance of morphologically altered cells which express several specific markers characteristic of differentiated cells, suggesting that c-fos plays a role in cellular differentiation.Keywords
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