Biological half-time of cadmium in the blood of workers after cessation of exposure.

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Abstract
The biological half-time of Cd in the blood of previously exposed workers was estimated after the cessation of exposure. Five men were followed for 10-13 yr. One-compartment and 2-compartment exponential elimination models were used to describe the decrease in blood Cd levels over time. The best fit to the data was obtained with a 2-compartment model. The half-times estimated from this model ranged from 75-128 days for the fast component and from 7.4-16.0 yr for the slow component. There was a long whole-body biological half-time for Cd, and the estimated half-times were similar to those obtained with different methods.

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