A Comparison Of Measurement of Homovanillic Acid in Brain Tissue by Gas Chromatography Mass Spectrometry and Liquid Chromatography with Electrochemical Detection
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 15 (13) , 1099-1109
- https://doi.org/10.1080/00032718208064423
Abstract
A comparison of liquid chromatography with electrochemical detection (LCEC) and gas chromatography mass spectrometry (GCMS) has been made for analysis of homovanillic acid (HVA) in rat brain tissue. The LCEC procedure gave slightly higher average values of HVA in the samples measured; however, the HVA content determined by both methods related significantly. Rat brain meostriatum was used as representative samples for comparison of the two analytical procedures.Keywords
This publication has 7 references indexed in Scilit:
- Determination of dopamine, homovanillic acid and 3,4-dihydroxyphenylacetic acid in rat brain striatum by high-performance liquid chromatography with electrochemical detectionJournal of Chromatography B: Biomedical Sciences and Applications, 1981
- Regional rat brain levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid: concurrent fluorometric measurement and influence of drugsEuropean Journal of Pharmacology, 1976
- CEREBROSPINAL FLUID HOMOVANILLIC ACID AND ISO‐HOMOVANILLIC ACID: A GAS–LIQUID CHROMATOGRAPHIC METHODJournal of Neurochemistry, 1974
- Mass fragmentographic determination of homovanillic acid in tissues and body fluids using the deuterium labeled species as internal standardLife Sciences, 1973
- Amine Metabolites in Human Cerebrospinal Fluid: Effects of Cord Transection and Spinal Fluid BlockScience, 1973
- Gas-chromatographic determination of homovanillic acid in human cerebrospinal fluid by electron capture detection and by mass fragmentography with a deuterated internal standardAnalytical Chemistry, 1972
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951