Comparison of some permeability properties of rat liver slices, liver cells in suspension, andin vivo-produced aggregates of dispersed liver cells
- 1 December 1975
- journal article
- research article
- Published by Springer Nature in The Journal of Membrane Biology
- Vol. 22 (1) , 329-340
- https://doi.org/10.1007/bf01868178
Abstract
It has been reported earlier that when rat liver is dispersed to a single cell suspension, the parenchymal cells lose the ability to take up pyrimidine bases but acquire the ability to take up RNAase and macromolecular nucleic acids. It is now shown that these changes are largely reversed on intraperitoneal reaggregation of the parenchymal cells and that, in these respects, the aggregates behave more like the organized tissue than like the dispersed cells.Keywords
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