Inactivation of the gene (cpe ) encoding Clostridium perfringens enterotoxin eliminates the ability of two cpe‐positive C. perfringens type A human gastrointestinal disease isolates to affect rabbit ileal loops
Open Access
- 1 September 1999
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 33 (5) , 946-958
- https://doi.org/10.1046/j.1365-2958.1999.01534.x
Abstract
Previous epidemiological studies have implicated Clostridium perfringens enterotoxin (CPE) as a virulence factor in the pathogenesis of several gastrointestinal (GI) illnesses caused by C. perfringen...Keywords
This publication has 34 references indexed in Scilit:
- VIRULENCE GENES OFCLOSTRIDIUM PERFRINGENSAnnual Review of Microbiology, 1998
- Phenotypic Characterization of EnterotoxigenicClostridium perfringensIsolates from Non-foodborne Human Gastrointestinal DiseasesAnaerobe, 1998
- Beta2 toxin, a novel toxin produced by Clostridium perfringensGene, 1997
- Molecular variation between the α-toxins from the type strain (NCTC 8237) and clinical isolates of Clostridium perfringens associated with disease in man and animalsMicrobiology, 1996
- Virulence studies on chromosomal α‐toxin and Θ‐toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of α‐toxin in Clostridium perfringens‐mediated gas gangreneMolecular Microbiology, 1995
- Construction of a sequencedClostridium perfringens-Escherichia coli shuttle plasmidPlasmid, 1992
- Toxigenic clostridiaClinical Microbiology Reviews, 1990
- Development and application of an enzyme linked immunosorbent assay for Clostridium perfringens type A enterotoxin.Journal of Clinical Pathology, 1985
- Regional Localization of Activity of Clostridium perjringens Type A Enterotoxin in the Rabbit Ileum, Jejunum, and DuodenumThe Journal of Infectious Diseases, 1977
- Experimental Diarrhoea in Human Volunteers Following Oral Administration of Clostridium perfringens EnterotoxinJournal of Applied Bacteriology, 1977