Xeroderma pigmentosum groups C and F: Additional assignments and a review of the subjects in Japan.
Open Access
- 1 January 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Radiation Research
- Vol. 26 (4) , 443-449
- https://doi.org/10.1269/jrr.26.443
Abstract
The differential bead-labelling method for heterodikaryon complementation enabled us to allocate xeroderma pigmentosum patients XP40KO and XP38KO to complementation groups C and F, respectively. Group C XP40KO cells exhibited 15% UDS and the 5 and 1.5-fold hypersenstivities to UV and 4-nitroquinoline-1-oxide (4NQO) killings, respectively, while group F XP38KO cells showed a higher residual level of 20-25% UDS and a less UV/4NQO hypersensitivity than did the previously assigned group F strains. We reviewed the thus far assigned Japanese groups C and F subjects for the repair and clinical characteristics. The present group C XP40KO was typical, while XP38KO was heterogrnous within group F with respect to repair.This publication has 8 references indexed in Scilit:
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