DETECTION OF RESPIRATORY MECHANICAL DYSFUNCTION BY FORCED RANDOM NOISE IMPEDANCE PARAMETERS

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Abstract
Respiratory mechanical parameters were computed from forced random noise impedance data in normal adults (group 1), asymptomatic smokers (group 2) and patients with obstructive pulmonary disease (group 3). Mean values for all derived parameters were significantly different (P < 0.025) for group 3. Mean values of resonant frequency, the ratio of low-frequency (5-9 Hz) resistance to high frequency resistance (15-19 Hz), and conductance normalized by height were significantly different (P < 0.05) between groups 1 and 2. Apparently this approach yields respiratory mechanical parameters that are sensitive to mechanical alterations induced by early pulmonary disease. The rapid, noninvasive and effort-independent nature of this approach make it especially useful for epidemiologic studies and for noncooperative subject studies.

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