SANGUINARINE, A PHOTOTOXIC H2O2‐PRODUCING ALKALOID
- 1 December 1989
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 50 (6) , 733-738
- https://doi.org/10.1111/j.1751-1097.1989.tb02903.x
Abstract
— Sanguinarine chloride, a quaternary salt of a benzophenanthrene alkaloid, was phototoxic to catalase‐deficient strains of Escherichia coli but not to Trichoplusia ni (cabbage looper moth larvae), an insect with high levels of catalase activity. Chemical analyses confirm that sanguinarine is an efficient producer of H2O2. This differential toxicity suggests that the mode of phototoxic action involves production of H2O2 which could be detoxified in many organisms by catalase.This publication has 31 references indexed in Scilit:
- β‐CARBOLINE ALKALOIDS: MECHANISMS OF PHOTOTOXICITY TO BACTERIA AND INSECTSPhotochemistry and Photobiology, 1988
- Using Bacterial Mutants and Transforming DNA To Define Phototoxic MechanismsPublished by American Chemical Society (ACS) ,1987
- Sanguinarine: its potential, as a liver toxic alkaloid present in the seeds ofArgemone mexicanaCellular and Molecular Life Sciences, 1985
- Mutation induction by 365-nm radiation and far-ultraviolet light in Escherichia coli strains differing in near- and far-ultraviolet light sensivity☆Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1984
- Berberine: A naturally occurring phototoxic alkaloidJournal of Chemical Ecology, 1984
- Production of singlet oxygen and superoxide radicals by psoralens and their biological significanceBiochemical and Biophysical Research Communications, 1983
- GENETIC CONTROL OF NEAR‐UV (300–400nm) SENSITIVITY INDEPENDENT OF THE recA GENE IN STRAINS OF ESCHERICHIA COLI K12Photochemistry and Photobiology, 1979
- Sanguinarine, inhibitor of NaK dependent ATP'aseBiochemical and Biophysical Research Communications, 1975
- Comparison of two transformation systems for the assay of theNeurosporaphotoreactivating enzymeGenetics Research, 1972
- A procedure for the isolation of deoxyribonucleic acid from micro-organismsJournal of Molecular Biology, 1961