Eosinophils and basophilic cells in sputum and nasal smears taken from infants and young children during acute asthma

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Abstract
To examine the increase in eosinophils and basophilic cells in the respiratory areas of infants and young children with asthma (n= 111), we analyzed the numbers of eosinophils and basophilic cells in sputum and nasal smears. The number of children with eosinophilia grades of 2+ or greater (> = 11 cells/five fields in x 1000 magnification) in sputum and nasal smears, respectively, in each age group was as follows: 33% and 21% under 1 year, 59% and 64% at 1 year, and 79–80% and 75–78% at 2–3 years. An increased infiltration of basophilic cells according to age was also observed. Infiltration of these cells began earlier than the appearance of IgE antibodies to mite in blood.