High-resolution footprints of the DNA-binding domain of Epstein-Barr virus nuclear antigen 1.
Open Access
- 1 June 1989
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 9 (6) , 2738-2742
- https://doi.org/10.1128/mcb.9.6.2738
Abstract
The DNA-binding domain of Epstein-Barr virus nuclear antigen 1 was found by hydroxyl radical footprinting to protect backbone positions on one side of its DNA-binding site. The guanines contacted in the major groove by the DNA-binding domain of Epstein-Barr virus nuclear antigen 1 were identified by methylation protection. No difference was found in the interaction of the DNA-binding domain of Epstein-Barr virus nuclear antigen 1 with tandemly repeated and overlapping binding sites.This publication has 18 references indexed in Scilit:
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