Bacterial Flora in Chronic Prostatitis

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Abstract
Bacteriologic studies were made in 105 cases of chronic prostatitis at the Mayo Clinic during a period of 5 mos. Organisms were found in cultures of prostatic secretions in 96 (91%) of these cases. Many different bacteria were isolated from these prostatic secretions; 36% were regarded as pathogenic, 5% were possibly pathogenic and 59% nonpathogenic. Cultures were made from specimens of urine collected at the same time as the prostatic secretions. Of the total number of pathogens present in cultures of prostatic secretions, 58% appeared in cultures of urine from these same patients. Only 16% of the 80 "nonpathogenic" bacteria obtained from pro_ static secretions appeared in the urine. The majority of patients who had "pathogenic" organisms in both prostatic secretions and urine had symptoms that warranted a trial of chemotherapy. A considerable number of patients had no organisms in the prostatic secretion or had organisms that were regarded as insignificant bacteriologically. Patients in these groups would be expected to derive little, if any, benefit from chemotherapy.

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