Predictors of Overall and Cancer-Free Survival of Patients With Localized Prostate Cancer Treated With Primary Androgen Suppression Therapy: Results From the Prostate Cancer Outcomes Study
- 30 April 2007
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 177 (4) , 1307-1312
- https://doi.org/10.1016/j.juro.2006.11.054
Abstract
Conclusions The use of primary androgen suppression therapy in the Prostate Cancer Outcomes Study data set resulted in 91% 5-year cancer specific survival. Advanced age, and factors that reflect tumor burden and biology were predictive of overall survival, while cancer specific survival was predicted by tumor factors and the burden of comorbid conditions. A nomogram for predicting overall survival at 5 years was constructed.Keywords
This publication has 18 references indexed in Scilit:
- Androgen‐deprivation therapy as primary treatment for localized prostate cancerCancer, 2006
- Cancer Statistics, 2006CA: A Cancer Journal for Clinicians, 2006
- Increasing use of gonadotropin‐releasing hormone agonists for the treatment of localized prostate carcinomaCancer, 2005
- National Practice Patterns and Time Trends in Androgen Ablation for Localized Prostate CancerJNCI Journal of the National Cancer Institute, 2003
- Three‐month neoadjuvant hormonal therapy before radical prostatectomy: a 7‐year follow‐up of a randomized controlled trialBJU International, 2002
- The Current State of Hormonal Therapy for Prostate CancerCA: A Cancer Journal for Clinicians, 2002
- Factors Associated With Initial Therapy for Clinically Localized Prostate Cancer: Prostate Cancer Outcomes StudyJNCI Journal of the National Cancer Institute, 2001
- Updated results of the phase III Radiation Therapy Oncology Group (RTOG) trial 85-31 evaluating the potential benefit of androgen suppression following standard radiation therapy for unfavorable prognosis carcinoma of the prostateInternational Journal of Radiation Oncology*Biology*Physics, 2001
- Immediate Hormonal Therapy Compared with Observation after Radical Prostatectomy and Pelvic Lymphadenectomy in Men with Node-Positive Prostate CancerNew England Journal of Medicine, 1999
- Improved Survival in Patients with Locally Advanced Prostate Cancer Treated with Radiotherapy and GoserelinNew England Journal of Medicine, 1997