Influence of decontamination of the digestive tract on the urinary excretion of histamine and some of its metabolites
- 1 October 1984
- journal article
- research article
- Published by Springer Nature in Inflammation Research
- Vol. 15 (3-4) , 238-241
- https://doi.org/10.1007/bf01972355
Abstract
Urinary excretions of histamine, Nt-methylhistamine and Nt-methylimidazoleacetic acid have been determined for 8 healthy volunteers during 14 consecutive days. Selective decontamination of the digestive tract was performed from day 3 to day 6, followed by total decontamination from day 7 to day 10. Urinary excretions of Nt-methylhistamine and Nt-methylimidazoleacetic acid decreased to a small though significant degree (about 15–20%) after total decontamination, suggesting a histamine production by anaerobic bacteria. Cadaverine decreased for about 70% under both selective and total decontamination, suggesting that this amine in human urine mainly originates from aerobic bacteria in the intestinal tract.This publication has 17 references indexed in Scilit:
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