The Selective Liquid-Phase Oxidation of 3,4,5-Trimethoxytoluene to 3,4,5-Trimethoxybenzaldehyde
- 1 March 1988
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 61 (3) , 1035-1037
- https://doi.org/10.1246/bcsj.61.1035
Abstract
The selective liquid-phase oxidation of 3,4,5-trimethoxytoluene to 3,4,5-trimethoxybenzaldehyde, an important chemical intermediate for medicine production, was developed; when 2.0 mmol of the reactant was heated at 110°C for 2 h in an autoclave under 3 atm O2 with 10 ml of acetic acid in the presence of 0.75 mmol of Co(OAc)2–Mn(OAc)2 (3:1 mole ratio), a 92% yield of the aldehyde was obtained.This publication has 2 references indexed in Scilit:
- The Liquid-Phase Oxidation of p-Methoxytoluene to p-Anisaldehyde with Co(OAc)2/Ce(OAc)3/Cr(OAc)3 CatalystBulletin of the Chemical Society of Japan, 1988
- Present aspect and possibilities of electroorganic synthesis from the viewpoint of industrial use. Trend in patent applications.Journal of Synthetic Organic Chemistry, Japan, 1985