A Rapid, Sensitive, and Specific Screening Technique for the Determination of Cyanide

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Abstract
A colorimetric method for the screening of cyanide in biological specimens is presented. Cyanide in a 200 µL sample is diffused in a Conway 3 compartment dish into the center well where it catalyzes the reaction between p-nitrobenzaldehyde and o-dinitrobenzene. The resulting blue-violet color intensity is proportional to cyanide concentration. The reaction is specific for cyanide, and concentrations as low as 0.05 mg/L can readily be detected.

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